Publications
Responses of an In Vitro Coculture Alveolar Model for the Prediction of Respiratory Sensitizers (ALIsens®) Following Exposure to Skin Sensitizers and Non-Sensitizers
Sabina Burla, Aline Chary, Tommaso Serchi, Sébastien Cambier, Kristie Sullivan, Elizabeth Baker, Nikaeta Sadekar and Arno C. Gutleb.
Comparison of the biological impact of aerosol of e-vapor device with MESH® tech and cigarette smoke on human bronchial and alveolar cultures.
Giralt, A., Iskandar, A., Martin, F., Moschini, E., Serchi, T., Kondylis, A., Marescotti, D., Leroy, P., Ortega-Torres, L., Majeed, S., Merg, C., Trivedi, K., Guedj, E., Frentzel, S., Ivanov, N.V., Peitsch, M.C., Gutleb, A.C., Hoeng, J. 2021.
Pro-inflammatory effects of crystalline and nano-sized non-crystalline silica particles in a 3D alveolar model.
Skuland, T., Låg, M., Gutleb, A.C., Brinchmann, B., Serchi, T., Øvrevik, J., Holme, J.A., Refsnes, M. 2020.
An improved in vitro coculture system for the detection of respiratory sensitizers.
Chary, A., Serchi, T., Moschini, E., Hennen, J., Cambier, S., Ezendam, J., Blömeke, B., Gutleb, A.C. 2019.
In vitro exposure of a 3D-tetraculture representative for the alveolar barrier at the air-liquid interface to silver particles and nanowires.
Fizeșan, I., Cambier, S., Moschini, E., Chary, A., Nelissen, I., Ziebel, J., Audinot, J.-N., Wirtz, T., Kruszewski, M., Kiss, B., Pop, A., Serchi, T., Loghin, F., Gutleb, A.C. 2019.
How complex should an in vitro model be? Evaluation of a complex 3D alveolar model with transcriptomic data and computational biological network models.
Marescotti, D., Serchi, T., Luettich, K., Xiang, Y., Moschini, E., Talikka, M., Martin, F., Baumer, K., Dulize, R., Peric, D., Bornard, D., Guedj, E., Sewer, A., Cambier, S., Contal, S., Chary, A., Gutleb, A.C., Frentzel, S., Ivanov, N.V., Peitsch, M.C., Hoeng, J. 2019.
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway.
Brinchmann, B.C., Skuland, T., Rambøll, M.H., Szoke, K., Brinchmann, J.A., Gutleb, A.C., Moschini, E., Kubátová, A., Kukowski, K., Le Ferrec, E., Lagadic-Gossmann, D., Schwarz, P.E., Låg, M., Refsnes, M., Øvrevik, J., Holme J.A. 2018.
Respiratory sensitization: toxicological point of view on the available assays.
Chary, A., Hennen, J., Klein, S., Serchi, T., Gutleb, A.C., Blömeke, B. 2018.
Responsiveness assessment of a 3D tetra-culture alveolar model exposed to diesel exhaust particulate matter.
Fizeșan, I., Chary, A., Cambier, S., Moschini, E., Serchi, T., Nelissen, I., Kiss, B., Pop, A., Loghin, F., Gutleb, A.C. 2018.
Air–Liquid Interface In Vitro Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations.
Lacroix, G., Koch, W., Ritter, D., Gutleb, A.C., Larsen, S.T., Loret, T., Zanetti, F., Constant, S., Chortarea, S., Rothen-Rutishauser, B., Hiemstra, P., Frejavon, E., Hubert, P., Gribaldo, L., Kearns, P., Aublant, J.-M., Angeloni, S., Diabaté, S., Weiss, C., de Groot, A., Kooter, I. 2018.
Endothelial responses of the alveolar barrier in vitro in a dose-controlled exposure to diesel exhaust particulate matter.
Klein, S.G., Cambier, S., Hennen, J., Legay, S., Serchi, T., Nelissen, I., Chary, A., Moschini, E., Krein, A., Blömeke, B., Gutleb, A.C. 2017.
An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung.
Klein, S., Serchi, T., Hoffmann, L., Blömeke, B., Gutleb, A.C. 2013.
Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung.
Klein, S., Hennen, J., Serchi, T., Blömeke, B., Gutleb, A.C. 2011.
Downscaling of a Three-Dimensional Alveolar In Vitro Model for High-Throughput Screening of Inhalable Respiratory Sensitizers in the Food Industry
Sabina BURLA1, 2, 3, Aline CHARY1, Elisa MOSCHINI1, Charlotte B. A. STOFFELS1,4,5, Tommaso SERCHI1, Carmen SOCACIU2, Mihai A. SOCACIU6*, Arno C. GUTLEB1,3*
New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation
Lynne T. Haber 1 *, Mark A. Bradley 1 , Amanda N. Buerger 2†, Holger Behrsing 3 , Sabina Burla 4 , Phillip W. Clapp 5†, Scott Dotson 6 , Casey Fisher 7, Keith R. Genco 8, Francis H. Kruszewski 9, Shaun D. McCullough 10†, Kathryn E. Page 11 , Vivek Patel 3, Nathan Pechacek 7†, Clive Roper 12, Monita Sharma 13 and Annie M. Jarabek 14
