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description: Respiratory Toxicology Insights | Inhalation Safety Research
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# [How complex should an in vitro lung model be? Evaluation of a complex 3D alveolar model](https://invitrolize.com/blog/how-complex-should-an-in-vitro-lung-model-be)

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 by[invitrolize](https://invitrolize.com/blog/author/invitrolize)   
Mar 13, 2026, 11:16:51 AM

Introduction In inhalation toxicology, more complexity is often assumed to mean more relevance. That assumption is convenient, but not always correct. Every extra cell type added to an in vitro model ...

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[![](https://invitrolize.com/hs-fs/hubfs/Post%20cleaning%20products.webp?width=500&height=500&name=Post%20cleaning%20products.webp) in vitro assessment of cleaning products for respiratory irritation Respiratory sensitization remains one of the most difficult endpoints in inhalation toxicology. For industry, the real challenge is not only identifying whether an inhaled substance is hazardous, but distinguishing a true respiratory sensitizer from a simple irritant. That distinction matters: ... by invitrolize •Mar 12, 2026, 7:49:40 PM](https://invitrolize.com/blog/in-vitro-assessment-of-cleaning-products-for-respiratory-irritation)

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